Acute bacterial sinusitis: current concepts in antibiotic therapy

نویسندگان

چکیده

Acute rhinosinusitis is a widespread pathology faced by both outpatient doctors and otorhinolaryngologists in hospitals. At the same time, only understanding of principles for diagnosing various forms sinusitis, particular, criteria bacterial provides adequate treatment decisions. Antibacterial therapy plays key role patients with acute sinusitis. Additionally, there an increasing frequency antibiotic resistance main pathogens respiratory group diseases. Both Russian foreign clinical guidelines, so-called lines antibacterial are clearly identified. Strict adherence to national recommendations thorough analysis anamnestic data allows rational approach choice drug. There increase rate uncontrolled inadequate therapy, particularly using penicillins short course macrolides, over last decade. Such trend dangerous due increased risks development those groups antibiotics. Use dispersible one point strategies overcome resistance. The most important features antibiotics prevented destruction stomach maximal absorption upper parts small intestine. It bioavailability drug minimize impact on intestinal microbiome, which reduces incidence common adverse reactions from gastrointestinal tract. According literature, oral administration drugs reach plasma concentrations similar parenteral administration.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Acute bacterial sinusitis in children.

On the basis of strong research evidence, the pathogenesis of sinusitis involves 3 key factors: sinusostia obstruction, ciliary dysfunction, and thickening of sinus secretions. On the basis of studies of the microbiology of otitis media, H influenzae is playing an increasingly important role in the etiology of sinusitis, exceeding that of S pneumoniae in some areas, and b-lactamase production b...

متن کامل

Acute community-acquired bacterial sinusitis: continuing challenges and current management.

Acute sinusitis is one of the most common infections seen in general clinical practice. The most common cause of acute sinusitis is viral; however, many patients receive a prescription for an antibiotic. Such injudicious prescribing habits have a major impact on health care costs, contribute to the increasing prevalence of drug-resistant strains of common respiratory pathogens, and reflect many...

متن کامل

BACTERIAL ETIOLOGIES AND ANTIBIOTIC RESISTANCE IN SINUSITIS: A STUDY OF 264 CASES

Although inflammatory processes involving facial sinuses rarely develop during childhood, these antrums due to their anatomic situations are exposed to a variety of biologic and nonbiologic agents after birth. Many types of bacteria are able to initiate inflammatory responses in these antrums. Since effective management of these patients rests upon demonstration of a specific pathogen and ...

متن کامل

Current Antibiotic Therapy

competent to speak on hospitaf advances in Ulster without reference to this book; it should be in every doctor's library. It is an accurate unbiased survey of the first 75 years of this hospital when finances had to be found and fought for and when as yet the State had no control. Finally a book is often enhanced by its format, and Dr. Calwell is to be congratulated on the lay out and his choic...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: ??????????? ?????

سال: 2023

ISSN: ['0235-1188', '2618-8961']

DOI: https://doi.org/10.21518/ms2023-065